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Acrolein concentrations were determined every 40 min using IC-PAD and the highest acrolein concentrations determined were considered to be present in the first well and were used for the calculation of those acrolein present in other wells on 96-well plates: acrolein concentrations tested ranged from 1 to 735 M in reuterin solutions, from 2 to 645 M in 3-HPA solutions and from 3 to 1130 M in acrolein solutions

L-carnitine, crucial in fatty acid metabolism and often deficient in cirrhosis patients, significantly mitigated cramps at doses ranging from 300 mg twice daily to 1,200 mg/day